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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MOS All Species: 11.52
Human Site: S16 Identified Species: 21.11
UniProt: P00540 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P00540 NP_005363.1 346 37820 S16 P Y L R S E F S P S V D A R P
Chimpanzee Pan troglodytes XP_528144 346 37828 S16 P Y L R S E F S P S V D A R P
Rhesus Macaque Macaca mulatta XP_001087400 305 33010
Dog Lupus familis XP_544088 372 41133 S40 S Y L P S E F S P S V D S R P
Cat Felis silvestris
Mouse Mus musculus P00536 390 42872 V66 P R E L S P S V D S R S C S I
Rat Rattus norvegicus P00539 339 37603 P17 Y L P R E L S P T V D S R S C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P10741 349 38245 D20 L E L S P S A D L R P C S S P
Frog Xenopus laevis P12965 359 39143 S16 R F L P R D L S P S I D L R P
Zebra Danio Brachydanio rerio NP_991143 329 36509 F15 T R L L P K D F G L E F G A C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9U1Y5 476 53320 D60 R R G I S S I D L A D D H F V
Sea Urchin Strong. purpuratus XP_789415 418 47752 K30 Q A Y L Q R T K R T I S T E N
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130627 368 40934 G16 K S S G G G N G G G P G K R L
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q2MHE4 390 44263 E22 L R S K L P L E P S L P N L P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 85.5 78.4 N.A. 65.3 71 N.A. N.A. 62.1 53.7 46.5 N.A. N.A. N.A. 20.1 26.3
Protein Similarity: 100 99.4 86.4 83.5 N.A. 71.7 78.9 N.A. N.A. 72.7 66.5 62.1 N.A. N.A. N.A. 36.1 40.6
P-Site Identity: 100 100 0 80 N.A. 20 6.6 N.A. N.A. 13.3 46.6 6.6 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 100 0 86.6 N.A. 20 6.6 N.A. N.A. 20 66.6 13.3 N.A. N.A. N.A. 20 13.3
Percent
Protein Identity: N.A. 29.6 N.A. 22.8 N.A. N.A.
Protein Similarity: N.A. 43.2 N.A. 42 N.A. N.A.
P-Site Identity: N.A. 6.6 N.A. 20 N.A. N.A.
P-Site Similarity: N.A. 6.6 N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 0 0 8 0 0 16 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 16 % C
% Asp: 0 0 0 0 0 8 8 16 8 0 16 39 0 0 0 % D
% Glu: 0 8 8 0 8 24 0 8 0 0 8 0 0 8 0 % E
% Phe: 0 8 0 0 0 0 24 8 0 0 0 8 0 8 0 % F
% Gly: 0 0 8 8 8 8 0 8 16 8 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 0 16 0 0 0 8 % I
% Lys: 8 0 0 8 0 8 0 8 0 0 0 0 8 0 0 % K
% Leu: 16 8 47 24 8 8 16 0 16 8 8 0 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 8 % N
% Pro: 24 0 8 16 16 16 0 8 39 0 16 8 0 0 47 % P
% Gln: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 16 31 0 24 8 8 0 0 8 8 8 0 8 39 0 % R
% Ser: 8 8 16 8 39 16 16 31 0 47 0 24 16 24 0 % S
% Thr: 8 0 0 0 0 0 8 0 8 8 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 8 0 8 24 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 24 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _